This Handbook serves as a convenient, state-of-the-art and comprehensive resource on the pathogenesis, diagnosis, and treatment of glomerular diseases. Clinical approaches, modalities and challenges are provided, along with new developments since the publication of Kidney Disease Improving Global Outcomes (KDIGO): Glomerulonephritis.
Chapters dedicated to glomerular diseases mirror the current classification schemes used by Nephrologists and Pathologists and will include definition and natural history, epidemiology, clinical manifestations, pathology, diagnosis, differential diagnosis, treatment (algorithms when appropriate), prognosis and future prospects and current direction of research.
Contributing authors consist of internationally renowned glomerulonephritis experts, renal pathologists and clinical nephrologists who are engaged in the management of glomerular diseases in clinical pediatric and internal medicine practices.
Glomerulonephritis fills a considerable knowledge gap for general nephrologists, providers involved with the care of patients with glomerular diseases, and researchers. It should also be of value to medical students, interns, residents and fellows, as well as all clinicians engaged in medical education.
General Overview.- Niddk Perspective On Current Status And Future Of Glomerular Disease Research.- Glomerular Physiology.- Mechanisms Of Disease.- Diagnostic Tests.- Histopathology.- Approach To A Renal Biopsy.- Classification Of Diseases.- Overview Of Current Approaches To Classification.- Rationale For Scheme Used In This Book.- Discussion Of Overlap Entities.- Integration With Kdigo.- Glomerular Diseases.- Podocytopathies.- Minimal Change Disease.- Focal Segmental Glomerulosclerosis.- Genetic Disorders.- Alport.- Nail Patella.- Auto-Immune.- Lupus Nephritis Including Antiphospholipid Antibody Syndrome.- Anti-Pla2r/Anti-Thrombospondin Type 1 Domain Containing 7a.- Membranous Nephropathy.- Anca-Associated Vasculitis.- Anti-Gbm Antibody Disease/Goodpasture.- Immune Complex-Mediated Diseases.- Iga Nephropathy And Henoch-Schőnlein Nephritis.- Membranoproliferative Glomerulonephritis, Type I.- Secondary Membranous Nephropathy.- Post-Infectious Gn.- Cryoglubulinemic Glomerulonephritis, Type Ii.- Infection Associated Glomerulonephritis.- Hepatitis B And C.- Hivan.- Other Infectious-Associated Gn.- Paraprotein Diseases Of The Kidney.- Renal Amyloidosis.- Midd.- Immunotactoid Glomerulopathy.- Waldenstrőm Macroglobulinemia.- Complement Mediated Diseases.- C3 Glomerulonephritis.- Dense Deposit Disease (Mpgn Type Ii) .- Thrombotic Microangiopathies.- Hemolytic Uremic Syndrome.- Thrombotic Thrombocytopenic Purpura.- Glomerulonephritis Associated With Other Systemic Diseases And Drugs.- Malignancies.- Medications.- Rheumatic Diseases.- Transplantation Related.- Pregnancy.- Additional Idiopathic Glomerular Diseases.- Fibronectin Glomerulopathy.- Collagenofibrot Ic Glomerulopathy.
Howard Trachtman, MD, is Professor of Pediatrics at NYU School of Medicine. He is the Director of the Division of Pediatric Nephrology, NYU Langone Health. Dr. Trachtman has authored numerous peer-reviewed articles, reviews, and book chapters focusing on glomerular disease and hypertension. He has been the principle investigator for a wide range NIH- and Industry-sponsored clinical trials in glomerular disease and a co-investigator in the NEPTUNE and CureGN observational cohort studies.
Leal C. Herlitz, MD, is the director of the renal pathology division at the Cleveland Clinic. She is an experienced academic renal pathologist and has published numerous original articles and book chapters in the field of renal pathology, primarily focused on glomerular disease.
Edgar V. Lerma is Clinical Professor of Medicine at the University of Illinois at Chicago College of Medicine. He is Educational Coordinator for the Section of Nephrology at UIC/ Advocate Christ Medical Center in Oak Lawn, IL. He has authored more than 100 publications and presentations; notable publications which he edited include Current Diagnosis & Treatment: Nephrology & Hypertension, Nephrology Secrets and Henrich’s Principles and Practice of Dialysis. He has peer reviewed and served on editorial boards for numerous journals, and currently serves as Associate Editor for Clinical Reviews in Bone and Mineral Metabolism, Reviews in Endocrinology and Metabolic Disorders, and Journal of Clinical Lipidology. He serves as Visual Abstract editor for the Clinical Journal of the American Sociaety of Nephrology (CJASN) and Section Editor for Geriatric Nephrology for International Urology and Nephrology medical journal. Dr. Lerma’s clinical and research interests include CKD, hypertension, bone and mineral disorders, and dyslipidemias in CKD. He is also actively involved with nephrology related social Media projects such as #Nephpearls, #NephJC (Online Journal Club) and #Nephmadness.
Jonathan J. Hogan, MD, attended medical school at the University of Pennsylvania in Philadelphia. He completed his residency training in Internal Medicine at the Hospital of the University of Pennsylvania, and his fellowship in Nephrology at Columbia University Medical Center in New York. Following fellowship, Dr. Hogan completed a fellowship in glomerular diseases at Columbia under the mentorship of Dr. Gerald Appel. In 2014, Dr. Hogan returned to Philadelphia as an Assistant Professor of Medicine at the Pereleman School of Medicine, University of Pennsylvania. He is also the Clinical Director of the Penn Glomerular Disease Center. Dr. Hogan has authored numerous peer-reviewed articles and book chapters, and has spoken a multiple invited lectures nationwide, with a focus on glomerular disease and onco-nepharology. He is also site-principal investigator or co-investigator on multiple NIH- and industry-sponsored studies in glomerular disease.
State-of-the-art resource on the pathogenesis, diagnosis, and treatment of glomerular diseases
Covers the latest clinical approaches and advances in research
Authored by internationally renowned glomerulonephritis experts, renal pathologists and clinical nephrologists
State-of-the-art and comprehensive resource on the pathogenesis, diagnosis, and treatment of glomerular diseases
Covers the latest clinical approaches and advances in research
Authored by internationally renowned glomerulonephritis experts, renal pathologists and clinical nephrologists