This book presents as teaching files a collection of cases of thyroid and parathyroid diseases seen at various high-volume endocrinology centers. The cases, most of which are accompanied by instructive images, have been selected in order to impart clinically relevant knowledge on the full range of endocrine disorders of thyroid and parathyroid origin. Accordingly, the book covers not only situations that are frequently encountered by the clinician in primary care, but also uncommon disorders and unusual presentations of common disorders. The comprehensive nature of the coverage will assist in resolving diagnostic dilemmas, and the reader will also find up-to-date information on disease management. The recommendations provided are based on current evidence-based clinical practice guidelines and are supported by relevant literature so as to harmonize available evidence-based protocols with current clinical practice. Thyroid and Parathyroid Diseases: A Case-Based Guide is designed to be thought provoking and to aid knowledge retention. Written by renowned experts in nuclear medicine, clinical endocrinology, oncology, and general surgery, it will appeal to specialists and residents in these fields.
PART I. Benign Thyroid Diseases
Chapter 1. Amiodarone induced thyrotoxicosis in a case with multinodular goiter
Chapter 2. Factitious hyperthyroidism
Chapter 3. Management of Resistant Hyperthyroidism Following Obesity Surgery
Chapter 4. Toxic multinodular goiter in a patient who has been followed up with the diagnosis of Hashimoto Thyroiditis and has normal TSH values
Chapter 5. Acut suppurative thyroiditis
Chapter 6. Graves Ophtalmopathy
Chapter 7. Surgery in Graves disease
Chapter 8. Surgery in Hyperthyrodism: Toxic adenoma and/or multinodular goiter
Chapter 9. A Case of Sarcoidosis, Differentiated Thyroid Carcinoma, and Graves’ Disease in the Thyroid Gland
Chapter 10. A patient presenting with an incidentally found hypermetabolic thyroid nodule on FDG-PET/CT
Chapter 11. Management of a thyroid nodule hypoactive on thyroid scintigraphy and has egg shell calcification on USG
Chapter 12. Percutaneous ethanol injection in a patient with cystic thyroid nodule
Chapter 13. Fibrin injection in hemorrhagic cystic thyroid nodule
Chapter 14. Should calcitonin be measured in every thyroid nodule ?
Chapter 15. The role of thyroid scintigraphy in the evaluation of thyroid nodules in patients with normal TSH
Chapter 16. Incidentally detected thyroid follicular adenoma on myocard perfusion scintigraphy with Tc-99m MIBI
Chapter 17. Follicular neoplasia
Chapter 18. A gray zone in thyroid fine-needle aspiration cytology: AUS-FLUS
Chapter 19. Is surgery the treatment of choice for every thyroid nodule?
Chapter 20. Follow-up of nodular-multinodular goiter: When should the operation be performed?
Chapter 21. Recurrent Nodular Goiter
Chapter 22. Intrathoracic goiter
Chapter 23. Persistent hypothyroidism despite Levothyroxine replacement therapy: Malabsorption or patient noncompliance
Chapter 24. Malpractice and ethical violations in thyroid and parathyroid surgery
Chapter 25. Application of Ultrasound by the Surgeon in Thyroid-Parathyroid Surgery
Chapter 26. Intraoperative nerve monitorization
Chapter 27. Recurrent Laryngeal Nerve Injury in Thyroid Surgery with Intraoperative Nerve Monitoring
PART II. Thyroid Cancer
Chapter 28. Preoperative cervical US mapping in a patient undergoing thyroidectomy for malignant cytologic findings
Chapter 29. Papillary Thyroid Carcinoma and Microcarcinoma
Chapter 30. A patient presented with extensive lung metastases of papillary carcinoma without any primary focus detected on total thyroidectomy
Chapter 31. Thyrotoxicosis caused by functioning metastases of differentiated thyroid cancer
Chapter 32. Papillary thyroid carcinoma
Chapter 33. Papillary thyroid carcinoma with central lymph node metastases
Chapter 34. A case of Papillary Cancer of the Thyroid with Minimal Extra-thyroidal Extension
Chapter 35. Therapeutic Neck Dissection for differentiated thyroid cancer: To Whom and To What Extent?
Chapter 36. Prophylactic unilateral neck dissection for differentiated thyroid cancer
Chapter 37.Surgical treatment of locally advanced papillary thyroid cancer
Chapter 38. Completion thyroidectomy in a patient with differentiated thyroid cancer
Chapter 39. 18F-FDG PET/CT in the initial staging of differentiated thyroid cancer
Chapter 40. A Case of a Papillary Thyroid Cancer with Gross Residual Disease After Surgery
Chapter 41. The effect of positive surgical margins after thyroidectomy on patient prognosis in cases with differentiated thyroid carcinoma
Chapter 42. Low-dose radioiodine therapy in well differentiated carcinoma
Chapter 43. Dosimetric approach in metastatic differentiated thyroid cancer and hyperthyroidism
Chapter 44. Anti-thyroglobulin antibody positivity during follow-up of a patient with differentiated thyroid cancer
Chapter 45. A patient with differentiated thyroid cancer with Tg values constantly above normal but not increasing gradually
Chapter 46. A Patient with Papillary Thyroid Carcinoma and biochemical incomplete response with gradually increasing Tg values and negative imaging studies
Chapter 47. Rosiglitazone effect on radioiodine uptake in a case of dedifferentiated thyroid carcinoma
Chapter 48. Management of recurrent lymph nodes in central and lateral neck in the follow up of differentiated thyroid carcinoma
Chapter 49. Minimally invasive follicular carcinoma
Chapter 50. Follicular thyroid cancer and bone metastasis
Chapter 51. Differentiated thyroid cancer and brain metastasis
Chapter 52. Differentiated thyroid cancer and pulmonary metastasis
Chapter 53. Targeted systemic therapy may be promising in radioiodine refractory differentiated thyroid cancer
Chapter 54. Targeted systemic therapy in patients with radioiodine refractory differentiated thyroid cancer
Chapter 55. Thyroid Follicular Carcinoma with Iodine-Avid Bone Metastases Showing Mild Uptake on Both 18F-FDG and 68Ga-DOTATOC PET/CT
Chapter 56. Somatostatin receptor imaging in Differentiated Thyroid Cancer
Chapter 57. Anaplastic carcinoma
Chapter 58. The Clinical Management of a Patient with Insular Thyroid Carcinoma
Chapter 59. Prophylactic and therapeutic surgery in familial medullary thyroid cancer
Chapter 60. Sporadic Medullary Cancer
Chapter 61. Concurrent papillary thyroid cancer and medullary thyroid cancer
Chapter 62. Medullary Thyroid Carcinoma
Chapter 63. Hurthle cell carcinoma
Chapter 64. Thyroid lymphoma
Chapter 65. Radioiodine therapy during breastfeeding
Chapter 66. A child with Papillary Thyroid Carcinoma: Role of Radioactive Iodine Therapy in pediatric patients
Chapter 67. Pediatric PTC with diffuse lung metastases: pulmonary function testing and steroid therapy prior to RAI
PART III. Parathyroid diseases
Chapter 68. Ectopic parathyroid adenoma
Chapter 69. Parathyroid adenoma which was negative on Tc99m-MIBI scintigraphy and considered as paratracheal lymphadenopathy on other imaging studies
Chapter 70. Brown tumor due to primary hyperparathyroidism disguised as lung cancer in a patient with rib lesions
Chapter 71. Radiofrequency ablation in a patient with primary hyperparathyroidism
Chapter 72. Clinical usefulness of an intraoperative “quick parathyroid hormone” measurement in primary hyperparathyroidism management
Chapter 73. Robot-assisted Endoscopic Mediastinal Parathyroidectomy
Chapter 74. Focused parathyroidectomy
Chapter 75. Subtotal glandectomy in Hyperparathyroidism
Chapter 76. Success of reoperative neck surgery in persistent hyperparathyroidism
Chapter 77. Postoperative hyperparathyroidism in differentiated thyroid cancer
Tamer Özülker, MD, is Associate Professor of Nuclear Medicine at the University of Health Sciences (SBÜ), Okmeydanı Training and Research Hospital, İstanbul, Turkey. He is a graduate of the Medical School of the University of Hacettepe, Ankara and completed his nuclear medicine residency at Okmeydanı Training and Research Hospital. Dr. Özülker has published a number of peer-reviewed scientific articles in high-impact journals and is a co-editor of the 2015 Springer book Atlas of PET-CT Imaging in Oncology – A Case-Based Guide to Image Interpretation as well as a previous Atlas of Bone Scintigraphy. He serves as associate editor of the Okmeydanı Medical Journal. His clinical and research interests include PET-CT, PET-MRI, and thyroid diseases.
Mine Adaş, MD, is Associate Professor of Endocrinology and Metabolism at the University of Health Sciences (SBÜ), Okmeydanı Training and Research Hospital, İstanbul, Turkey. She is a graduate of the Istanbul University School of Medicine. She completed her internal medicine residency at Okmeydanı Training and Research Hospital and then undertook her endocrinology training at Istanbul University School of Medicine, where she became a qualified endocrinologist in the year 2000. Dr. Adas has published a number of peer-reviewed scientific articles. Her clinical and research interests include thyroid, parathyroid, and suprarenal diseases. She is a member of the Turkish Society of Endocrinology and Metabolism, the Stem Cell and Stem Cell Therapy Association, and the European Society of Endocrinology and Endocrine Society.
Semra Günay, MD, is a specialist in breast and endocrine surgery who currently works at the University of Health Sciences (SBÜ), Okmeydanı Training and Research Hospital, İstanbul, Turkey. She is a graduate of the Istanbul University School of Medicine and completed her general surgery residency in the same faculty. She has published a number of peer-reviewed scientific articles and is one of the authors of the Turkish language book Trauma (ISBN 9789756395240). Dr. Günay has participated in the educational work of the Turkish Surgical Association and has worked as an instructor on postgraduate training courses in the field of endocrine surgery. She is coordinator and founder of İstanbul Endocrine Meetings (ISTET) and member of editorial board of Okmeydanı Medical Journal.
This book presents as teaching files a collection of cases of thyroid and parathyroid diseases seen at various high-volume endocrinology centers. The cases, most of which are accompanied by instructive images, have been selected in order to impart clinically relevant knowledge on the full range of endocrine disorders of thyroid and parathyroid origin. Accordingly, the book covers not only situations that are frequently encountered by the clinician in primary care, but also uncommon disorders and unusual presentations of common disorders. The comprehensive nature of the coverage will assist in resolving diagnostic dilemmas, and the reader will also find up-to-date information on disease management. The recommendations provided are based on current evidence-based clinical practice guidelines and are supported by relevant literature so as to harmonize available evidence-based protocols with current clinical practice. Thyroid and Parathyroid Diseases: A Case-Based Guide is designed to be thought provoking and to aid knowledge retention. Written by renowned experts in nuclear medicine, clinical endocrinology, oncology, and general surgery, it will appeal to specialists and residents in these fields.
Presents a collection of cases of thyroid and parathyroid diseases seen at high-volume endocrinology centers
Provides the practitioner with clinically relevant information in the context of the case histories
Covers rarely encountered cases as well as situations frequently encountered in primary care
Aids in diagnosis and treatment decision making based on evidence-based guidelines
