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Pre-Clinical and Clinical Methods in Brain Trauma Research

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EAN: N/A SKU: 9781493993277 Categories: ,

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Weight 751 g
Dimensions 178 × 254 mm
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About The Author

Srivastava, Amit K.

This volume explores current viewpoints and knowledge gaps in the field of traumatic brain injury (TBI). The chapters in this book cover topics ranging from development of in vitro and animal TBI models, to diagnostic imaging and disease monitoring in patients. Designing pre-clinical and clinical trials is also discussed. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.
Practical and thorough, Pre-Clinical and Clinical Methods in Brain Trauma Research is a valuable resource for both scientists and clinical researchers interested in learning about important techniques and their applications in the field of TBI.
Series Preface…
Preface…
Table of Contents…
Contributing Authors…
 
1. Traumatic Brain Injury
 Amit K. Srivastava and Charles S. Cox, Jr.
2. Three-Dimensional In Vitro Brain Tissue Models
Min D. Tang-Schomer
3. Modeling Traumatic Brain Injury In Vitro
Daniel E. Bonder, Carolyn E. Keating, Namas Chandra, D. Kacy Cullen, and Bryan J. Pfister

4. Drosophila Model to Study Chronic Traumatic Encephalopathy

Rojahne Azwoir and Liam Chen
5. Controlled Cortical Impact for Modeling Traumatic Brain Injury in Animals
Nicole Osier and C. Edward Dixon
6. Fluid Percussion Model of Traumatic Brain Injury
Rachel K. Rowe, Daniel Griffiths, and Jonathan Lifshitz
7. Development of a Rodent Model of Closed Head Injury: The Maryland Model 
Erik Hayman, Kaspar Kaledjian, Vladimir Gerzanich, and J. Marc Simard
8. Rodent Model of Primary Blast-Induced Traumatic Brain Injury: Guidelines to Blast Methodology
Venkatasivasai Sujith Sajja, Arun Peethambaram, Stephen A. Van Albert, and Joseph B. Long
9. Cognitive and Motor Function Assessments in Rodent Models of Traumatic Brain Injury
Danielle Scott and Kathryn E. Saatman 

10. Pre-Procedural Considerations and Post-Procedural Care for Animal Models with Experimental Traumatic Brain Injury

Mary A. Robinson, Samer M. Jaber, Stacey L. Piotrowski, and Thomas H. Gomez
11. Laser Capture Microdissection of Single Cells, Cell Populations, and Brain Regions Affected by Traumatic Brain Injury
Harris A. Weisz, Deborah R. Boone, Stacy L. Sell, and Helen L. Hellmich

12. Rat Microglia Isolation and Characterization Using Multi-Parametric Panel for Flow Cytometric Analysis
Naama E. Toledano Furman, Karthik S. Prabhakara, Supinder Bedi, Charles S. Cox Jr., and Scott D. Olson
13. The Principles of Experimental Design and the Determination of Sample Size When Using Animal Models of Traumatic Brain Injury  

Michael F.W. Festing

14. Advanced Informatics Methods in Acute Brain Injury Research
Jude P.J. Savarraj, Mary F. McGuire, Ryan Kitagawa, and Huimahn Alex Choi
15. Rapid Detection and Monitoring of Brain Injury Using Sensory Evoked Responses

Jonathan A. N. Fisher and Cristin G. Welle 

16. Advanced Neuroimaging Methods in Traumatic Brain Injury
Jenifer Juranek
17. Dynamic Contrast Enhanced MRI for the Analysis of Blood-Brain Barrier Leakage in Traumatic Brain Injury  

Qiang Shen and Timothy Q. Duong 

18. Assessments for Quantifying Neuromotor Functioning after Repetitive Blast Exposure
Christopher K. Rhea, Nikita A. Kuznetsov, W. Geoff Wright, F. Jay Haran, Scott E. Ross, and Josh L. Duckworth
19. Translingual Neurostimulation (TLNS): Perspective on a Novel Approach to Neurorehabilitation after Brain Injury
Yuri Danilov and Dafna Paltin
20. The Rapid Templating Process for Large Cranial Defects
Jeremy Kwarcinski, Philip Boughton, Andrew Ruys, and James van Gelder
21. Computer-Assisted Approaches to Identify Functional Gene Networks Involved in Traumatic Brain Injury
Anthony San Lucas, John Redell, Pramod Dash, and Yin Liu
22. Clinical Trials for Traumatic Brain Injury: Designs and Challenges
Juan Lu and Mirinda Gormley 

“This is a well-organized book of neuromethods in brain trauma intended for trainees in the laboratory … . The combination of excellent reviews of experimental procedures, clinical information, and detailed protocols will be helpful for graduate students, postdocs and neurosurgery residents. Additionally, clinicians and clinician scientists involved in translational research should find this volume especially useful.” (Bruce G. Lyeth, Neurosurgery, Vol. 85 (1), July, 2019)

This volume explores current viewpoints and knowledge gaps in the field of traumatic brain injury (TBI). The chapters in this book cover topics ranging from development of in vitro and animal TBI models, to diagnostic imaging and disease monitoring in patients. Designing pre-clinical and clinical trials is also discussed. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.
Practical and thorough, Pre-Clinical and Clinical Methods in Brain Trauma Research is a valuable resource for both scientists and clinical researchers interested in learning about important techniques and their applications in the field of TBI.

Includes cutting-edge methods and protocols
Provides step-by-step detail essential for reproducible results
Contains key notes and implementation advice from the experts