This book describes the pathogenesis and treatment of several representative hematological disorders in children, with a special focus on genetic and molecular aspects. Research on the pathogenesis of hematological disorders in children has made remarkable strides; especially molecular target therapy has shown outstanding effects in refractory and conventional therapies for childhood leukemia. The findings presented in this book will broaden readers’ understanding and hopefully spark new discussions leading to the development of new therapies including cell therapy and molecular target therapy, allowing clinicians to use more effective and less toxic approaches in the future.
Hematological Disorders in Children will appeal to a wide readership, from medical students and beginning investigators to experienced scholars in the field of pediatric hematology and oncology seeking to broaden their understanding and keep up with the latest developments. It will also be of interest to the parents of pediatric patients, and to co-medical staffs.
Part 1 Introduction
1 Hematopoietic Stem Cells
Part 2 White Blood Cell Disorders
2 Acute Lymphoblastic Leukemia (including Infant Leukemia)
3 Acute Myeloid Leukemia
4 Myelodysplastic Disease (including JMML)
5 Leukopenia
Part 3 Red Blood Cell Disorders
6 Aplastic Anemia
7 Hemolytic Anemia
Part 4 Platelet and Coagulation Disorders
8 Immune and inherited thrombocytopenia
9 Hemophilia
10 Thrombosis
Part 5 Histiocytic Disorders
11 Langerhans Cell Histiocytosis
12 Hemophagocytic Lymphohistiocytosis, primary
13 Hemophagocytic Lymphohistiocytosis, secondary
“This unique treatise describes the pathogenesis and treatment modalities of childhood hematologic disorders that are both currently in use and that show future promise. … The intended audience includes not only medical specialists who are involved in treating pediatric patients, but also medical students, research scientists, and even parents of afflicted children who can gain some perspective on the complexities of these disorders and the progress being made to treat them.” (Ravi Salgia, Doody’s Book Reviews, April, 2018)
“A concise treatise which in 3 chapters divided into 3 parts summarizes present knowledge on hematological diseases in childhood. With illustrations, tables and many references. For pediatricians in practice and in training.” (Pediatric Endocrinology Reviews, Vol. 15 (2), December, 2017)
Editor: Dr Eiichi Ishii, Department of Pediatrics, Ehime University Graduate School of Medicine, Toon, Japan
This book describes the pathogenesis and treatment of several representative hematological disorders in children, with a special focus on genetic and molecular aspects. Research on the pathogenesis of hematological disorders in children has made remarkable strides; especially molecular target therapy has shown outstanding effects in refractory and conventional therapies for childhood leukemia. The findings presented in this book will broaden readers’ understanding and hopefully spark new discussions leading to the development of new therapies including cell therapy and molecular target therapy, allowing clinicians to use more effective and less toxic approaches in the future.
Hematological Disorders in Children will appeal to a wide readership, from medical students and beginning investigators to experienced scholars in the field of pediatric hematology and oncology seeking to broaden their understanding and keep up with the latest developments. It will also be of interest to the parents of pediatric patients, and to co-medical staffs.
Describe the pathogenesis and treatment of several representative hematological disorders in children
Special focus on the genetic and molecular aspects of childhood hematological disorders
Broadens readers’ understanding and will spark new discussions
Valuable resource for medical students, beginning investigators, and experienced scholars in the field of pediatric hematology and oncology
