Osteoporosis is the most common bone disease and is associated with pathological fractures that can lead to significant morbidity. It represents an economic burden to the health care system, directly linked to an ageing population. Guidelines on osteoporosis prevention have been published but these do not provide the required specialised knowledge for the treating physician. This book ‘fills the gap’ and focuses on the principles of surgical and medical treatment of osteoporosis. It aims to improve education and provide answers based on current evidence, helping doctors follow best practice, improve patient care and outcomes, and minimise the complications of medical and surgical management.
Contributors
1. Definition, risk factors, and epidemiology of osteoporosis
Enrique Guerado and Enrique Caso
2. Pathogenesis: Molecular mechanisms of osteoporosis
Anastasia E. Markatseli, Theodora E. Markatseli, and Alexandros A. Drosos
3. Osteoporosis: Biochemical investigations
Ippokratis Pountos and Peter V. Giannoudis
4. Diagnosis: Radiological investigations
David J. Hak and Rodrigo Banegas
5. Development of a fragility liaison service
Paul Andrzejowski and Peter V. Giannoudis
6. NICE guidelines for medical treatment of osteoporosis: An update
Katherine Lowery and Nikolaos K. Kanakaris
7. Role of bisphosphonates and denosumab
Blossom Samuels, Yi Liu, and Joseph Lane
8. The role of anabolic agents
Nifon K. Gkekas, Eustathios Kenanidis, Panagiotis Anagnostis, Michael Potoupnis, Dimitrios G. Goulis, and Eleftherios Tsiridis
9. Current and emerging pharmacological agents in the treatment of osteoporosis
James X. Liu and Thomas A. Einhorn
10. Monitoring/surveillance of medical treatment
Konstantinos D. Stathopoulos and Andreas F. Mavrogenis
11. Systemic complications of osteoporosis medical treatment
Konstantinos G. Makridis and Stamatina-Emmanouela Zourntou
12. Complications of medical treatment: Atypical fractures
Owen Diamond, Natalie C. Rollick, and David L. Helfet
13. Biomechanical considerations for fixation of osteoporotic bone
Peter Augat and Christian von Rüden
14. The fix and treat principle: An update
Vasileios P. Giannoudis and Peter V. Giannoudis
15. Principles of management of osteoporotic fractures
Seth M. Tarrant and Zsolt J. Balogh
16. Can we accelerate the osteoporotic bone fracture healing response?
Martijn van Griensven and Elizabeth Rosado Balmayor
17. Management of osteoporotic proximal humeral fractures: An overview
J.P.A.M. Verbruggen
18. Distal humerus fractures in the elderly: To fix or to replace?
Jon B. Carlson, Craig S. Roberts, and David Seligson
19. Distal radius osteoporotic features: My preferred method of treatment
Donato Perretta and Jesse B. Jupiter
20. Management of osteoporotic pelvic fractures
Pol M. Rommens, Daniel Wagner, and Alexander Hofmann
21. Management of osteoporotic acetabular fractures: Fix or replace?
Peter V. Giannoudis and Panagiotis Douras
22. Management of osteoporotic proximal intertrochanteric/subtrochanteric femoral fractures
Avadhoot Kantak and George Tselentakis
23. Osteoporotic distal femoral fractures: When to fix and how
Cyril Mauffrey and Nicholas A. Alfonso
24. Osteoporotic distal femoral fractures: When to replace and how
Richard Stange and Michael J. Raschke
25. Osteoporotic long bone fractures: My preferred method of treatment
Sascha Halvachizadeh and Hans-Christoph Pape
26. Management of osteoporotic extra-articular proximal tibial fractures
Daniela Sanchez, Amrut Borade, and Daniel S. Horwitz
27. Osteoporotic ankle fractures: Principles of treatment
Theodoros H. Tosounidis and Michael G. Kontakis
28. Treatment of distal intra-articular/extra-articular tibial fractures
Vasileios P. Giannoudis and Peter V. Giannoudis
29. Osteoporotic os calcis fractures: How I manage them
Angus Jennings and Richard Buckley
30. Current trend in kyphoplasty for osteoporotic vertebral fractures
Kalliopi Alpantaki, Georgios Vastardis, and Alexander G. Hadjipavlou
31. Osteoporotic thoracolumbar fractures: My preferred method of nonoperative treatment
Terence Ong and Opinder Sahota
32. Augmentation of fracture fixation: An update
Peter V. Giannoudis and Panagiotis Douras
33. Complications of surgical treatment for osteoporotic fractures
Paul C. Baldwin III and Christian Krettek
34. Total shoulder replacement and osteoporosis: An Update
David Limb
35. Total hip replacement and osteoporosis: Current trends
Antonios Koutalos, Georgios Komnos, and Theofilos Karachalios
36. Total knee replacement and osteoporosis: An overview
Edward S. Holloway and Veysi T. Veysi
37. Rehabilitation of the osteoporotic patient: Is it different?
Theodoros H. Tosounidis and Amy Margot Lindh
Index
Peter V. Giannoudis is Professor at the School of Medicine, University of Leeds and Honorary Consultant at Leeds General Infirmary (LGI).
Thomas A. Einhorn, MD, is Professor of Orthopedic Surgery at New York University.
